Medical School MD + DO Mastery

A 4-year, board-aligned study system for medical school and licensing exams.

Walk the full Year 1–4 curriculum — foundational sciences, organ-system blocks, clinical clerkships and advanced practice — each with mastery checklists and linked learning resources, plus a dedicated review system for school exams, Shelf/COMAT, USMLE Step 1–3 and COMLEX-USA Levels 1–3.

NEUROLOGIC LOCALIZATION + ACUTE DISEASE

YEAR 2 | PAGE 26E - STROKE, SEIZURE, HEADACHE + LOCALIZATION

LOCALIZE BEFORE DIAGNOSING DEFICIT -> NEUROANATOMIC LEVEL -> SIDE -> VASCULAR / ELECTRICAL / STRUCTURAL MECHANISM -> TEST -> THERAPY. Before naming a

disease, decide cortex vs subcortex vs brainstem vs spinal cord vs peripheral nerve/NMJ/muscle; then use time course and focality to narrow the mechanism.

1

Stroke Syndromes: MCA, ACA, ICA, PCA + Vertebrobasilar - Ninja Nerd~1 hr 17
Maps vascular territories to motor, sensory, language, visual, brainstem and cerebellar deficits; excellent for lesion localization before memorizing stroke labels.

2

Acute Ischemic Stroke - Ninja Nerd~1 hr 15
Ischemic core/penumbra, thrombotic vs embolic mechanisms, imaging sequence, reperfusion logic, complications and secondary prevention.

3

Seizures + Status Epilepticus - Ninja Nerd~1 hr 41
Focal vs generalized seizure classification, clinical semiology, EEG/diagnostic reasoning, treatment and status epilepticus priorities.

4

Migraine Medications + Mechanism - Ninja Nerd~41 min
Trigemino-vascular pathophysiology, acute vs preventive therapy, triptans/CGRP agents and contraindication logic for headache questions.

CLOSED-BOOK NEURO CHECK

  • Given a focal deficit, name the anatomic level and side before the diagnosis; then predict the vascular territory or tract involved.
  • For seizure questions, classify focal vs generalized, awareness, motor/nonmotor pattern, provoking cause and status risk before choosing a drug.
  • For headache, screen for red flags first: sudden thunderclap, fever/meningismus, focal deficit, papilledema, pregnancy/hypercoagulability, cancer/immunosuppression or new late-onset pattern.
  • Distinguish UMN, LMN, NMJ and muscle patterns using tone, reflexes, sensory findings, fatigability and distribution.