Medical School MD + DO Mastery

A 4-year, board-aligned study system for medical school and licensing exams.

Walk the full Year 1–4 curriculum — foundational sciences, organ-system blocks, clinical clerkships and advanced practice — each with mastery checklists and linked learning resources, plus a dedicated review system for school exams, Shelf/COMAT, USMLE Step 1–3 and COMLEX-USA Levels 1–3.

PHARMACOLOGY FOUNDATIONS

YEAR 1 | PAGE 14A - PK/PD + AUTONOMIC PHARMACOLOGY CONCEPT MASTERY

Make drugs predictable: TARGET/RECEPTOR -> SIGNAL/PHYSIOLOGIC EFFECT -> DOSE/EXPOSURE -> INDICATION -> TOXICITY/INTERACTION -> MONITORING/REVERSAL. Build the mechanism first; names become easier to retain afterward.

A. DEEP FOUNDATIONAL PHARMACOLOGY VIDEOS - DIRECT & PLAYABLE

Use long-form videos to build the model, then redraw the equations/receptor map from memory before questions.

A. DEEP FOUNDATIONAL PHARMACOLOGY VIDEOS - DIRECT & PLAYABLE

#VideoTimeWhyLink
1.Pharmacokinetics Part 1: Absorption & Distribution - Armando Hasudungan2026 visualRoutes, bioavailability, first-pass effect, protein binding and volume of distribution - the ADME scaffold before dosing calculations.Open →
2.Pharmacodynamics - Ninja Nerd~89 minReceptors, agonists/antagonists, potency, efficacy, therapeutic index and dose-response curves with mechanism-based practice.Open →
3.Pharmacokinetics: Drug Metabolism - Ninja Nerd~28 minPhase I/II biotransformation, CYP logic and patient factors that alter metabolism - essential for interactions and toxicity reasoning.Open →
4.Pharmacokinetics: Drug Clearance - Ninja Nerd~22 minClearance, half-life, first- vs zero-order elimination and organ dysfunction; converts PK equations into clinically predictable changes.Open →
5.Autonomic Pharmacology: Cholinergic Agonists - Ninja Nerd~77 minMuscarinic/nicotinic receptor physiology -> parasympathomimetics -> indications, adverse effects and antidote-style reasoning.Open →
6.Autonomic Pharmacology: Adrenergic Agonists - Ninja Nerd~106 minAlpha/beta receptor signaling -> sympathomimetics -> organ effects, indications and predictable adverse-effect patterns.Open →

FOUNDATIONAL CLOSED-BOOK CHECK

  • Calculate or predict bioavailability, Vd, clearance, half-life, loading/maintenance dosing and first- vs zero-order elimination.
  • Interpret dose-response curves: potency vs efficacy, partial agonism, competitive vs noncompetitive antagonism and therapeutic index.
  • For alpha/beta/muscarinic/nicotinic receptors, state location -> G protein/second messenger -> organ effect -> agonist/antagonist consequence.
  • Predict how renal/hepatic dysfunction, protein binding or CYP induction/inhibition changes exposure before memorizing a drug-specific fact. VIDEO-FIRST | SCHOOL-EXAM + BOARD-EXAM MASTERY