Medical School MD + DO Mastery

A 4-year, board-aligned study system for medical school and licensing exams.

Walk the full Year 1–4 curriculum — foundational sciences, organ-system blocks, clinical clerkships and advanced practice — each with mastery checklists and linked learning resources, plus a dedicated review system for school exams, Shelf/COMAT, USMLE Step 1–3 and COMLEX-USA Levels 1–3.

BIOSTATISTICS, EPIDEMIOLOGY & EVIDENCE-BASED MEDICINE

YEAR 1 | PAGE 17A - STUDY DESIGN, RISK + DIAGNOSTIC TEST CONCEPT MASTERY

THINK IN STRUCTURES, NOT FORMULAS

For every question identify DESIGN -> DIRECTION OF SAMPLING -> MEASURE OF ASSOCIATION -> BIAS/VALIDITY -> CLINICAL INTERPRETATION. For diagnostic tests, rebuild the 2x2 table before calculating.

A. CORE BIOSTATISTICS + EPIDEMIOLOGY VIDEOS - DIRECT & PLAYABLE

#VideoTimeWhyLink
1.Study Designs - Osmosis from Elsevier~13 minRCT, cohort, case-control, cross-sectional and ecologic designs organized by intervention, timing, sampling direction and what each can estimate.Open →
2.How to Solve USMLE Step 1 Biostatistics - Randy Neil, MDdeep conceptBoard-oriented foundation for 2x2 tables, study design identification, sensitivity/specificity and calculation strategy.Open →
3.Biostatistics Questions Fast - Randy Neil, MDquestion logicWorked questions that turn formulas into repeatable problem-solving moves; use after the core explanation to force active retrieval.Open →
4.Case-Control (Odds Ratio) vs Cohort (Relative Risk) - Randy Neil, MDstudy-design bridgeStart with how subjects were selected, then choose the measure: outcome-first -> odds ratio; exposure-first -> incidence and relative risk.Open →
5.Sensitivity, Specificity, PPV, NPV - Dirty Medicine~11 minClinical 2x2-table framework plus prevalence effects on predictive values; concise and highly reusable for school and board questions.Open →
6.Sensitivity and Specificity - StatQuest~12 min ENRICHMENTA second conceptual angle on true/false positives and cutoff tradeoffs; useful when definitions feel memorized but not intuitive.Open →

A. CORE BIOSTATISTICS + EPIDEMIOLOGY VIDEOS - DIRECT & PLAYABLE — CORE QUANTITATIVE CLOSED-BOOK CHECK

  • From a stem alone, distinguish RCT, cohort, case-control, cross-sectional and ecologic designs before looking at answer choices.
  • Rebuild a 2x2 table and derive sensitivity, specificity, PPV and NPV; predict how prevalence changes PPV/NPV without changing sensitivity/specificity.
  • Calculate and interpret incidence, prevalence, relative risk, odds ratio, attributable/absolute risk reduction and NNT/NNH.
  • State the direction of common biases and whether the error threatens internal validity, external validity or both. VIDEO-FIRST | SCHOOL-EXAM + BOARD-EXAM MASTERY