SCHOOL-EXAM + PROBLEM-SOLVING MASTERY
YEAR 1 | PAGE 14C - CALCULATIONS, CURVES, MECHANISMS, TOXICITY & INTERACTIONS
C. WHAT SCHOOL EXAMS COMMONLY REQUIRE
| Resource | Description | Link |
|---|---|---|
| PK / dosing | Calculate or infer bioavailability, Vd, clearance, half-life, steady state, loading/maintenance dose and first- vs zero-order elimination. | |
| PD / curves | Read log dose-response curves; distinguish potency from efficacy and full/partial agonists from competitive/noncompetitive antagonists. | |
| Autonomics | Translate receptor + G protein/second messenger into organ effect, then predict agonist/antagonist indications and adverse effects. | |
| Metabolism / interactions | Phase I vs II, CYP induction/inhibition, prodrugs, renal/hepatic impairment and protein binding -> change in drug level or effect. | |
| Drug-class mechanism | Identify target/receptor/enzyme/channel and predict downstream physiology before using disease-name or medication-name recognition. | |
| Safety / toxicology | Recognize signature toxicity, monitoring and classic reversal/antidote principles; distinguish pharmacodynamic from pharmacokinetic interactions. |
D. 7-DAY SCHOOL-EXAM REVIEW CYCLE
| Resource | Description | Link |
|---|---|---|
| Days 1-2 | PK/PD calculations + graphs. Rebuild equations and dose-response relationships from a blank page, then solve new problems. | |
| Days 3-4 | Autonomics + receptor signaling. Work organ-by-organ receptor predictions before attaching drugs to the map. | |
| Day 5 | Metabolism/interactions + antimicrobials. Practice CYP, clearance and resistance-mechanism vignettes. | |
| Day 6 | Cardio/renal + endocrine/CNS representative classes. Complete a timed mixed school-style block; classify every miss. | |
| Day 7 | Re-test misses on NEW curves/cases. Use one targeted video only if the mechanism remains unclear, then finish with a cumulative block. |
D. 7-DAY SCHOOL-EXAM REVIEW CYCLE — E. PHARMACOLOGY ERROR-LOG TAXONOMY
- PK-equation gap - knew the formula but chose the wrong variable, units, direction or clinical interpretation.
- Receptor/signaling gap - memorized the drug but not the receptor, second messenger or organ-level consequence.
- MOA-to-effect gap - knew the target yet could not predict why it helps the disease or causes the adverse effect.
- Interaction/metabolism gap - missed how CYP, renal/hepatic function, protein binding or another drug changes exposure/effect.
- Class-confusion gap - mixed agents within a family because learning depended on names instead of the shared mechanism and discriminators.
D. 7-DAY SCHOOL-EXAM REVIEW CYCLE — SCHOOL-EXAM GATE
Proceed when you can solve unseen PK/PD graphs and dosing problems, infer drug effects from receptor/organ physiology, explain interactions mechanistically, and distinguish related drug classes using target + physiologic consequence rather than isolated memorization. VIDEO-FIRST | SCHOOL-EXAM + BOARD-EXAM MASTERY