MOLECULAR BIOLOGY + GENETICS CONCEPT MASTERY
YEAR 1 | PAGE 9B - DNA -> RNA -> PROTEIN -> INHERITANCE -> DIAGNOSIS
Mechanism sequence: DNA ORGANIZATION -> REPLICATION/REPAIR -> TRANSCRIPTION/PROCESSING -> TRANSLATION -> MUTATION -> INHERITANCE -> PHENOTYPE -> TEST SELECTION. Do not memorize disorders before you can explain this chain.
B. MOLECULAR + GENETICS VIDEOS - DIRECT & PLAYABLE
| # | Video | Time | Why | Link |
|---|---|---|---|---|
| 1. | DNA Replication - Ninja Nerd | ~67 min | Origins, helicase, primase, polymerases, leading/lagging strands, proofreading, telomeres and mutation risk. | Open → |
| 2. | DNA Transcription - Ninja Nerd | ~85 min | Promoters, polymerases, transcription factors, 5' cap/poly-A/splicing and prokaryotic-vs-eukaryotic regulation. | Open → |
| 3. | Translation: Protein Synthesis - Ninja Nerd | ~93 min | Genetic code, tRNA charging, ribosomes, initiation/elongation/termination and clinically relevant translation inhibitors. | Open → |
| 4. | Mendelian Genetics & Punnett Squares - Osmosis from Elsevier | visual concept | A current visual refresher on alleles, genotype/phenotype, dominance/recessiveness and probability before pedigree work. | Open → |
| 5. | Inheritance Patterns - Osmosis from Elsevier | ~10 min | Autosomal dominant/recessive, X-linked and mitochondrial inheritance with pedigree logic and disease examples. | Open → |
| 6. | Karyotyping - Osmosis from Elsevier | visual concept | Aneuploidy and structural chromosome abnormalities; connect test modality to what it can and cannot detect. | Open → |
B. MOLECULAR + GENETICS VIDEOS - DIRECT & PLAYABLE — GENETICS / MOLECULAR SCIENCE MASTERY CHECK
- Explain DNA replication, transcription and translation in the correct 5'->3' directions, including the main enzymes and regulatory steps.
- Solve autosomal dominant/recessive, X-linked and mitochondrial probability problems without pattern-name guessing.
- Distinguish penetrance, expressivity, anticipation, mosaicism, imprinting, heterogeneity and uniparental-disomy concepts.
- Choose conceptually among karyotype, FISH, microarray, PCR, sequencing and repeat-expansion testing based on the lesion being sought. VIDEO-FIRST | SCHOOL-EXAM + BOARD-EXAM MASTERY