Medical School MD + DO Mastery

A 4-year, board-aligned study system for medical school and licensing exams.

Walk the full Year 1–4 curriculum — foundational sciences, organ-system blocks, clinical clerkships and advanced practice — each with mastery checklists and linked learning resources, plus a dedicated review system for school exams, Shelf/COMAT, USMLE Step 1–3 and COMLEX-USA Levels 1–3.

SYSTEMS PHYSIOLOGY + HOMEOSTASIS

YEAR 1 | PAGE 11B - ACID-BASE, ENDOCRINE, ECG & METABOLIC SIGNALING

Integrate rather than silo: lungs alter CO2, kidneys alter H+/HCO3-, endocrine signals alter transport/metabolism, and cardiovascular flow determines delivery. JJ Medicine is used here as a targeted enrichment source where its focused signaling/transport videos add value.

B. SYSTEMS-INTEGRATION VIDEOS - CORE + ENRICHMENT

#VideoTimeWhyLink
1.Acid-Base Disorders - Ninja Nerd~92 minMetabolic/respiratory acidosis and alkalosis, anion gap, compensation and diagnostic approach from mechanism to clinical interpretation.Open →
2.Pancreas Overview: Insulin & Glucagon - Ninja NerdendocrineBeta/alpha-cell signaling, fed/fasted integration and the physiologic logic underlying diabetes and hypoglycemia.Open →
3.Synthesis of Thyroid Hormone - Ninja NerdthyroidIodide uptake, organification, coupling, T3/T4 release, TSH regulation and drug targets within normal thyroid physiology.Open →
4.Cardiovascular | EKG Basics - Ninja NerdECG bridgeElectrical axis, intervals and waveform logic that ties cardiac electrophysiology to clinical rhythm interpretation.Open →
5.Insulin Signaling Cascade & Downstream Effects - JJ MedicineENRICHMENTReceptor tyrosine-kinase signaling, PI3K/AKT pathway and downstream metabolic effects - a focused enrichment bridge from endocrine signaling to metabolism.Open →
6.Glucose Transporters (GLUTs and SGLTs) - JJ MedicineENRICHMENTTransporter distribution, insulin dependence and tissue-specific glucose handling - useful for endocrine, renal and metabolic integration.Open →

B. SYSTEMS-INTEGRATION VIDEOS - CORE + ENRICHMENT — SYSTEMS-INTEGRATION CHECK

  • Solve primary acid-base disorder -> expected compensation -> mixed disorder -> likely physiologic cause.
  • Use feedback-loop logic for pituitary, thyroid, adrenal and pancreatic hormones rather than memorizing isolated hormone lists.
  • Interpret ECG intervals/waves from underlying conduction and action-potential physiology.
  • Explain how insulin signaling and tissue-specific glucose transport change glucose handling in liver, muscle, adipose and kidney. VIDEO-FIRST | SCHOOL-EXAM + BOARD-EXAM MASTERY