Medical School MD + DO Mastery

A 4-year, board-aligned study system for medical school and licensing exams.

Walk the full Year 1–4 curriculum — foundational sciences, organ-system blocks, clinical clerkships and advanced practice — each with mastery checklists and linked learning resources, plus a dedicated review system for school exams, Shelf/COMAT, USMLE Step 1–3 and COMLEX-USA Levels 1–3.

ANTIMICROBIALS + SPECIAL INFECTIONS

YEAR 2 | PAGE 25F - RESISTANCE, HIV/VIROLOGY, FUNGI, TB + STI INTEGRATION

THERAPY FRAME

DRUG TARGET -> SPECTRUM -> SITE PENETRATION -> HOST FACTORS -> TOXICITY/INTERACTION -> RESISTANCE -> DE-ESCALATION. For HIV/OIs, pair immune status and CD4 pattern with organism, prophylaxis and treatment.

B. ANTIMICROBIAL + SPECIAL-INFECTION VIDEOS

#VideoTimeWhyLink
1.Antibiotics - Ninja Nerd~2 hr 18Mechanisms, spectrum, common empiric choices, toxicities, contraindications and major resistance mechanisms with cases.
2.Antivirals | HIV, Hepatitis, Influenza, Herpes - Ninja Nerd~1 hr 52HIV antiretroviral classes plus hepatitis, influenza and herpes drugs; mechanisms, adverse effects and treatment cases.
3.Antifungals - Ninja Nerd~46 minAzoles, amphotericin, echinocandins, terbinafine and others: targets, clinical use, adverse effects and case application.
4.Antimycobacterials | Anti-TB Drugs - Ninja Nerd~36 minRIPE-family mechanisms, clinical use, toxicities and case application; pair with the 2026 TB clinical lecture on 25E.
5.STI | Syphilis | Clinical Medicine - Ninja Nerd~1 hr 122026 lecture: stages, congenital disease, RPR/VDRL vs treponemal testing, neurosyphilis evaluation and penicillin therapy.
6.STI | Genital Herpes | Clinical Medicine - Ninja Nerd~59 min2026 lecture: HSV latency/reactivation, lesion patterns, diagnostic testing, antiviral therapy, pregnancy and neonatal risk.

B. ANTIMICROBIAL + SPECIAL-INFECTION VIDEOS — HIV / IMMUNOCOMPROMISED HOST CHECK

- Know the HIV replication targets used by NRTIs/NNRTIs, integrase inhibitors and protease inhibitors; recognize class-defining toxicities/interactions. - Use CD4 count + symptoms + imaging/lab pattern to prioritize opportunistic infections; know which prophylaxis and treatment principles are high yield. - In neutropenia, transplant or steroid exposure, widen the pathogen differential deliberately and recognize when fungal/viral disease becomes more likely. - For every antimicrobial miss, add mechanism, spectrum, signature toxicity, resistance mechanism and the infection where it is preferred to one table. VIDEO-FIRST | SCHOOL-EXAM + BOARD-EXAM MASTERY